Structural Biology Knowledgebase: An Integrated Resource for Modern Biologists

KBase: An Integrated Knowledgebase for Predictive Biology and Environmental Research

Systems Biology for Biologists

Do you avoid papers thick with mathematical details and unfamiliar statistical analyses? If so, this article is for you! Systems biology, at its core, is not a set of computational and mathematical techniques; these are merely tools, incredibly useful, but secondary. The heart of systems biology is simple: explaining how a system works requires an integrated outlook. For any phenotype—molecular...

A Modern Algebra for Biologists

Emphasized throughout this book is the idea that in vitro work has often thrown light upon an in vivo process or has indicated a new direction for in vivo study. It must be noted, however, that an in vitro situation is an artificial environment and care must be used in relating all such findings to the actual host-parasite relationship. In our age of molecular and submolecular microbiology, thi...

BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology

BacillOndex is an extension of the Ondex data integration system, providing a semantically annotated, integrated knowledge base for the model Gram-positive bacterium Bacillus subtilis. This application allows a user to mine a variety of B. subtilis data sources, and analyse the resulting integrated dataset, which contains data about genes, gene products and their interactions. The data can be a...

OpenStructure: an integrated software framework for computational structural biology

Research projects in structural biology increasingly rely on combinations of heterogeneous sources of information, e.g. evolutionary information from multiple sequence alignments, experimental evidence in the form of density maps and proximity constraints from proteomics experiments. The OpenStructure software framework, which allows the seamless integration of information of different origin, ...